Have you heard of actual evidence that people who have the virus are all totally immune to a second illness? I heard yesterday they are using the term 'may give immunity after being sick'. I dont know if the researchers have had time to follow up infected people to see if a secondary or tertiary human immune response will be basically immunity or a worse reaction leading to bad illness.
I mentioned this before but look up cytokine storm and I will paste info that the human body's reaction sometimes can be overblown causing extreme problems. A secondary response to the virus for some people can get out of hand. My wife the retired doctor tipped me off to this syndrome by name but I did know that secondary and tertiary immune response can get out of hand in humans. For most people they will probably have full to some sort of partial immunity with general sick symptoms but other people could have an overblown immune reaction and it is a crap shoot.
Cytokine release syndrome (
CRS) or
cytokine storm syndrome (
CSS) is a form of
systemic inflammatory response syndrome (SIRS) that can be triggered by a variety of factors such as infections and certain drugs.
[3] It occurs when large numbers of
white blood cells are activated and release
inflammatory cytokines, which in turn activate yet more white blood cells. CRS is also an
adverse effect of some
monoclonal antibody drugs, as well as
adoptive T-cell therapies.
[4][5] Severe cases have been called
cytokine storms.
[2] When occurring as a result of drug administration, it is also known as an
infusion reaction.
[1]
Contents
Signs and symptoms[edit]
Symptoms include fever, fatigue, loss of appetite, muscle and joint pain, nausea, vomiting, diarrhea, rashes, fast breathing, rapid heartbeat, low blood pressure, seizures, headache, confusion, delirium, hallucinations, tremor, and loss of coordination.
[4]
Lab tests and clinical monitoring show low blood oxygen, widened pulse pressure, increased cardiac output (early), potentially diminished cardiac output (late),
high levels of nitrogen compounds in the blood, elevated
D-dimer,
elevated transaminases,
factor I deficiency and excessive bleeding,
higher-than-normal level of bilirubin.
[4][6]
Cause[edit]
CRS occurs when large numbers of
white blood cells, including
B cells,
T cells,
natural killer cells,
macrophages,
dendritic cells, and
monocytes are activated and release
inflammatory cytokines, which activate more white blood cells in a positive feedback loop of pathogenic inflammation.
[4] Immune cells are activated by stressed or infected cells through receptor-ligand interactions.
[7]
This can occur when the
immune system is fighting
pathogens, as cytokines produced by immune cells recruit more effector immune cells such as
T-cells and inflammatory monocytes (which differentiate into
macrophages) to the site of inflammation or infection. In addition, pro-inflammatory cytokines binding their cognate receptor on immune cells results in activation and stimulation of further cytokine production.
[8] This process, when dysregulated, can be life-threatening due to systemic hyper-inflammation, hypotensive shock, and multi-organ failure.