I love that play and at the time it was amazing (he ran into the end zone I was seated in), but I would make this my #3 that I've seen in person. Tate to Holloway "The Catch" in the 2005 Capitol One Bowl is #1 and Murray's kick against PSU in 2008 is #2. this one is close to the other 2 and I could easily see it as #2, but Tate to Holloway was unbelievable. Also, Iowa @ MSU "7 got 6" in 2009 is a close #4, but with so few Iowa fans in the stadium the environment wasn't buzzing like it was at the Orange Bowl.
Side note ... my buddy had just purchased a brand new Orange Bowl T-Shirt at the stadium and had put it on right before kickoff. 10 seconds later, we were soaked in beer from everyone spraying it on each other. So much for a clean new shirt.