Last year Wyoming gave up an average of 34 points per game. Sure that includes 2 triple overtime games, but the point still stands that they gave up a lot of points. Nebraska hung 52 points on them thanks to 6 turnovers and 550 total yards.
I would not be surprised to see garbage touchdowns late by Wyoming to inflate their star QB's numbers and try to get the offense some confidence. However, I don't see how Wyoming stops Iowa's rushing attack.
Iowa wins 45-21. TD's by Fant, Wadley (2), Butler, Brandon Smith.