please 'splain it to the forum.
I'll let an expert do this:
One example is that Tuck more often has to use a stance with his shoulders square to the line of scrimmage, rather than on a tilt. It’s more of a read stance, he says, allowing players to read and react but also slowing down their get-off to the quarterback. This fits into what Umenyiora calls “slow-playing,†a necessary tactic to keep the quarterback in front of you.
Ends are also less able to make inside moves, Umenyiora explained, because mobile quarterbacks will see that and break contain around the edge or roll out to extend the play. And linebacker/defensive end Mathias Kiwanuka said they have to pay more attention to the “integrity†of the rush, in contrast to relying on athletic ability.
“There needs to be a wall of four people moving to the quarterback at the same speed at all times, otherwise he’ll find that small lateral or vertical crease, and he’ll run through it,†Kiwanuka said. “You just can’t go out there and give your best move or try to beat the man in front of you. All four guys have to play against all five guys (on the offensive line) at the same time.â€
This is one reason more teams are moving to a 3-4 right now. Now Old Guy is right in that you need the right support from the rest of your team. But I would put more emphasis on the safeties than the corners. If you can force a certain read in the pistol or run option, it might help your safeties be more read than react.