Looking at the entire KenPom era (back to 2002, total of 18 completed seasons), among the 72 Final Four teams, only three were outside the top 50 in defensive efficiency:
2012 VCU (78th)
2003 Texas (58th)
2003 Marquette (109th)
Iowa is currently 134th in defensive efficiency. To make the Final Four with this kind of profile would be *almost* unprecedented.
That 2003 Marquette team isn't a bad comp for this year's Iowa team. Obviously basketball has changed a lot since then, but the efficiency profiles are similar. They were 2nd in offensive efficiency (Iowa is still 1st), and led by a superstar (Dwyane Wade), but still had a pretty balanced attack (four starters in double figures scoring).
So overall there isn't a great precedent for an elite offense/mediocre-to-bad defense to make a run to the Final Four, but it wouldn't be *completely* unheard of...
2012 VCU (78th)
2003 Texas (58th)
2003 Marquette (109th)
Iowa is currently 134th in defensive efficiency. To make the Final Four with this kind of profile would be *almost* unprecedented.
That 2003 Marquette team isn't a bad comp for this year's Iowa team. Obviously basketball has changed a lot since then, but the efficiency profiles are similar. They were 2nd in offensive efficiency (Iowa is still 1st), and led by a superstar (Dwyane Wade), but still had a pretty balanced attack (four starters in double figures scoring).
So overall there isn't a great precedent for an elite offense/mediocre-to-bad defense to make a run to the Final Four, but it wouldn't be *completely* unheard of...