Conditioning might be a contributing factor against a team like MSU. By that, I don't mean this team isn't very well-conditioned, or that MSU's players are in better shape. They are simply able to wear us down physically on both ends of the floor because of their size and strength. It's no different than an offense in football using a power running game to wear down an opposing defense.
It was also Michigan State, and Bilas had a real point when he talked about this being a mental health game. We've lost 9 straight to MSU, and they're the only team in the Big Ten we haven't beaten since Fran's first year. The three losses before this one had come by a total of 8 points, which is enough "close, but yet so far's" to get into the heads of a lot of athletes. Last year's stretch run was a dumpster fire, but an anomaly of sorts, IMO. Once that train got started, there just wasn't any stopping it.
There's a bit of a mental block when it comes to closing out MSU, in particular. We've won close games against Wisconsin, Ohio State, North Carolina, Maryland and Virginia in just that past few years. MSU remains that one team that we just can't seem to get one over on, no matter what.